Anthony A. Hyman
(RA Leader)
MPI-CBG | Director of MPI-CBG, Professor for Molecular Cell Biology
Organization of Cytoplasm
Cells organize molecules into membraneless compartments. Biological condensates, for example, represent cellular phases that may emerge via liquid-liquid phase separation. However, the relationship between physical principles underlying compartment formation (such as phase separation), and the underlying molecular mechanisms, are unclear.
Our aim is to obtain a general understanding of the physical principles underlying the formation of membraneless compartments in cells and use these to understand regulation and function. At a biological level, we aim to reveal the mechanisms underlying the robust generation of distinct cell phases, via the formation of biomolecular condensates. At a physical level, we aim to understand how distinct phases are generated, controlled and maintained using the physics of active droplets and soft matter.
Research Topic 1
Emergent Physical Chemistry of Biomolecular Condensates
Research Topic 2
Protecting and Repairing DNA through condensates
Research Topic 3
Metabolic Condensates
Research Topic 4
Active Wetting in Cells
RA Leading Team
Simon Alberti
(RA Co-Leader)
TUD BIOTEC | Professor for Cellular Biochemistry
Organization of cytoplasm across space and time
© MPI-CBG
Ellen Adams
Research Group Leader
Physical Chemistry of Biomolecular Condensates
hired by PoL
PoL Groups
Ellen Adams
Research Group Leader
Physical Chemistry of Biomolecular Condensates
hired by PoL
Simon Alberti
TUD BIOTEC | Professor for Cellular Biochemistry
Organization of cytoplasm across space and time
© MPI-CBG
Jan Brugués
Chair of Spatiotemporal Organization of Subcellular Structures
Spatiotemporal Organization of Subcellular Structures
hired by PoL
Otger Campàs
Chair of Tissue Dynamics
Physics of Embryonic Self-Organization and Morphogenesis
hired by PoL
Stefan Diez
TUD B CUBE | Professor for BioNano Tools
Molecular transport in cell biology and nanotechnology
© TUD CMCB, Magdalena Gonciarz
Miki Ebisuya
Humboldt Professor and Chair of Cell and Tissue Control
Cross-Species Comparison and Manipulation of the Organoid Zoo
hired by PoL
Benjamin Friedrich
Heisenberg Professor for Biological Algorithms
Biological Algorithms: Spatio-Temporal Dynamics of Cells and Tissues
hired by PoL
Stephan W. Grill
MPI-CBG | Director of MPI-CBG, Professor for Physics of Life
Physics of Life
© MPI-CBG
Alf O. Honigmann
TUD BIOTEC | Professor for Biophysics
Membrane Organization of Cells and Tissues
Anthony A. Hyman
MPI-CBG | Director of MPI-CBG, Professor for Molecular Cell Biology
Organization of Cytoplasm
© Sven Döring
Marcus Jahnel
Research Group Leader
Dynamics of Biomolecules
hired by PoL
Frank Jülicher
MPI-PKS | Director of MPI-PKS, Professor for Biophysics
Dynamic processes in cells and tissues
© MPI-CBG
Ivo F. Sbalzarini
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
© MPI-CBG
Helmut Schießel
Chair of Theoretical Physics of Living Matter
Theoretical Physics of Living Matter
hired by PoL
Michael Schlierf
TUD B CUBE | Professor for Molecular Biophysics
Conformational changes in biomolecules and enzymes
© TUD CMCB, Magdalena Gonciarz
Jens-Uwe Sommer
IPF | Professor for Theory of Polymers at Interfaces
Theoretical Polymer Physics
© IPF, Jürgen Lösel
Ágnes Tóth-Petróczy
MPI-CBG | Research Group Leader
Protein plasticity and evolution
© MPI-CBG
Xingbo Yang
Research Group Leader
Bioenergetics of Self-Organization
hired by PoL
Associates and Affiliates
Anna Poetsch
TUD BIOTEC, NCT, CSBD | Research Group Leader
Biomedical Genomics
Alexander von Appen
MPI-CBG | Research Group Leader
Structural Self-Organization of Membranous Organelles
© MPI-CBG