Anne Grapin-Botton
(RA Leader)
MPI-CBG | Director of MPI-CBG
Self-organization of cells into organ communities
Tissue and organ formation relies on a hierarchy of processes that perform specific functions. These processes depend on tissue morphology, topology, as well as on physical and chemical characteristics. Physical and geometric tissue characteristics emerge from collective cellular behaviors and often involve qualitative changes in their collective states. These changes can be understood as collective transitions arising from cellular interactions and feedback.
Our aim is to reveal the physical principles that underlie the emergence of functional structures in living tissues. From a biological perspective, we will establish how tissue structure and function emerge from cell behaviors and their interactions. To achieve this result, concepts for collective transitions involving topology, energetics, mechanics, electricity and chemistry in active materials will be developed. A particular focus will be on how collective transitions govern the spatiotemporal organization of multicellular systems.
Research Topic 1
Topological Morphogenesis
Research Topic 2
Mechano-Electro-Chemical Self-Organization
Research Topic 3
Spatiotemporal Control of Tissue Material Transitions
Research Topic 4
Energy Flows and Metabolic Patterning in Morphogenesis
RA Leading Team
Otger Campàs
(RA Co-Leader)
Chair of Tissue Dynamics
Physics of Embryonic Self-Organization and Morphogenesis
hired by PoL
Catherina G. Becker
TUD CRTD, TUD Faculty of Biology | Professor for Neural Development and Regeneration
Neural Development and Regeneration
© TUD CMCB/Magdalena Gonciarz
Rita Mateus
Research Group Leader
Biophysical Principles of Vertebrate Growth
hired by PoL
PoL Groups
Ricard Alert
MPI-PKS, CSBD | Research Group Leader
The Physics of Living Matter
© MPI-CBG
Elias Barriga
Research Group Leader
Biophysical Mechanisms of Morphogenesis
hired by PoL
Catherina G. Becker
TUD CRTD, TUD Faculty of Biology | Professor for Neural Development and Regeneration
Neural Development and Regeneration
© TUD CMCB/Magdalena Gonciarz
Michael Brand
TUD CRTD | Professor for Developmental Genetics
Development and Regeneration of the Vertebrate Brain
Jan Brugués
Chair of Spatiotemporal Organization of Subcellular Structures
Spatiotemporal Organization of Subcellular Structures
hired by PoL
Otger Campàs
Chair of Tissue Dynamics
Physics of Embryonic Self-Organization and Morphogenesis
hired by PoL
Christian Dahmann
TUD | Professor for Systems Biology and Genetics
Signals and mechanics in epithelial morphogenesis
Adele Doyle
Research Group Leader
Mechanobiology of Stem Cells
hired by PoL
Miki Ebisuya
Humboldt Professor and Chair of Cell and Tissue Control
Cross-Species Comparison and Manipulation of the Organoid Zoo
hired by PoL
Elisabeth Fischer-Friedrich
Heisenberg Professor for Mechanics of Active Biomaterials
Mechanics of Active Biomaterials
hired by PoL
Benjamin Friedrich
Heisenberg Professor for Biological Algorithms
Biological Algorithms: Spatio-Temporal Dynamics of Cells and Tissues
hired by PoL
Anne Grapin-Botton
MPI-CBG | Director of MPI-CBG
Self-organization of cells into organ communities
© MPI-CBG
Stephan W. Grill
MPI-CBG | Director of MPI-CBG, Professor for Physics of Life
Physics of Life
© MPI-CBG
Heather Harrington
MPI-CBG, CSBD | Director of MPI-CBG and CSBD, Professor of Mathematics at the Mathematical Institute, University of Oxford
Algebraic Systems Biology
© Z Goriely
Alf O. Honigmann
TUD BIOTEC | Professor for Biophysics
Membrane Organization of Cells and Tissues
Meritxell Huch
MPI-CBG | Director of MPI-CBG, Lise Meitner Max Planck Research Group Leader
Organoids, tissue regeneration and its deregulation in disease
© MPI-CBG
Frank Jülicher
MPI-PKS | Director of MPI-PKS, Professor for Biophysics
Dynamic processes in cells and tissues
© MPI-CBG
Christina Kurzthaler
MPI-PKS, CSBD | Research Group Leader
Transport and Flows in Complex Environments
© MPI-CBG
Rita Mateus
Research Group Leader
Biophysical Principles of Vertebrate Growth
hired by PoL
Ivo F. Sbalzarini
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
© MPI-CBG
Carsten Werner
IPF | Professor for Biofunctional Polymer Materials
Biofunctional polymer materials
Xingbo Yang
Research Group Leader
Bioenergetics of Self-Organization
hired by PoL
Associates and Affiliates
Carl Modes
MPI-CBG | Research Group Leader
Network Complexity and Systems Biophysics
© MPI-CBG
Jonathan Rodenfels
MPI-CBG | Research Group Leader
Energetics of Biological Systems
© MPI-CBG
Pavel Tomancak
MPI-CBG | Research Group Leader
Patterns of gene expression in animal development
© MPI-CBG
Jesse Veenvliet
MPI-CBG | Research Group Leader
Stembryogenesis
© MPI-CBG
