Ivo F. Sbalzarini
(RA Leader)
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
PoL – Physics of Life | Vision and Research Avenues
Data-analysis and computational modeling play a fundamental role in linking theory and experiment. They help to generate testable hypotheses, interpret experimental data, study nonlinear models and are essential for testing the adequacy of physical theories. We envision novel computational methods, often based on AI algorithms, that are required to extract hidden patterns from data in the non-equilibrium, nonlinear, and multiscale systems studied at PoL.
Our aim will be to develop novel data analysis, Machine Learning, and scientific computing methods, with a focus on algorithmic innovations designed from the ground up, to cope with the complexity of living systems. We will integrate theory-driven numerical simulations with data-driven inference, resulting in physics-informed bio-data science. The mathematical foundations of topological data analysis will also be expanded, and used to understand these systems.
Research Topic 1
Revealing the High-Order Structures of Discrete Biological Data
Research Topic 2
Deep Learning for Biomolecular Grammar
Research Topic 3
Data-driven Modeling and Simulation
Research Topic 4
Bio-image Artificial Intelligence
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
© MPI-CBG
MPI-CBG, CSBD | Director of MPI-CBG and CSBD, Professor of Mathematics at the Mathematical Institute, University of Oxford
Algebraic Systems Biology
© Z Goriely
MPI-CBG | Research Group Leader
Protein plasticity and evolution
© MPI-CBG
TUD BIOTEC | Professor for Cellular Biochemistry
Organization of cytoplasm across space and time
© MPI-CBG
MPI-PKS, CSBD | Research Group Leader
The Physics of Living Matter
© MPI-CBG
Chair of Tissue Dynamics
Physics of Embryonic Self-Organization and Morphogenesis
hired by PoL
Research Group Leader
Mechanobiology of Stem Cells
hired by PoL
Heisenberg Professor for Biological Algorithms
Biological Algorithms: Spatio-Temporal Dynamics of Cells and Tissues
hired by PoL
MPI-CBG | Director of MPI-CBG
Self-organization of cells into organ communities
© MPI-CBG
MPI-CBG | Director of MPI-CBG, Professor for Physics of Life
Physics of Life
© MPI-CBG
MPI-CBG, CSBD | Director of MPI-CBG and CSBD, Professor of Mathematics at the Mathematical Institute, University of Oxford
Algebraic Systems Biology
© Z Goriely
TUD BIOTEC | Professor for Biophysics
Membrane Organization of Cells and Tissues
MPI-CBG | Director of MPI-CBG, Lise Meitner Max Planck Research Group Leader
Organoids, tissue regeneration and its deregulation in disease
© MPI-CBG
MPI-CBG | Director of MPI-CBG, Professor for Molecular Cell Biology
Organization of Cytoplasm
© Sven Döring
MPI-PKS | Director of MPI-PKS, Professor for Biophysics
Dynamic processes in cells and tissues
© MPI-CBG
MPI-PKS, CSBD | Research Group Leader
Transport and Flows in Complex Environments
© MPI-CBG
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
© MPI-CBG
TUD | Professor for Network Dynamics
Network Dynamics
MPI-CBG | Research Group Leader
Protein plasticity and evolution
© MPI-CBG
Research Group Leader
Bioenergetics of Self-Organization
hired by PoL
TUD BIOTEC, NCT, CSBD | Research Group Leader
Biomedical Genomics
MPI-CBG | Research Group Leader
Patterns of gene expression in animal development
© MPI-CBG
TUD | Professor for Scientific Computing and Applied Mathematics
Mathematical Modeling and Numerical Simulation of Cells and Systems
© MPI-CBG
MPI-CBG | Research Group Leader
Structural Self-Organization of Membranous Organelles
© MPI-CBG