Research Avenue 4

Fluxes, Fluctuations and the Emergence of Form

RA4 will reveal physical principles of organization that underlie the living state of matter. This research avenue will stimulate and aid RA1-3 by integrating the discoveries of RA1-3 in a more general context. We will bring concepts of non-equilibrium statistical physics and of nonlinear dynamics to the study of living matter. How are energy and matter fluxes patterned in space and time during morphogenesis? How can we integrate metabolic processes in a general theory of active matter? How can structures robustly arise in the presence of fluctuations and perturbations? How can cells reliably make decisions in light of fluctuations, perturbations and uncertainty? How does the genome encode shape and form in space and time? Which mechanisms allow for variations of shapes? Research in RA4 will bring understanding of how energy and matter fluxes are patterned in space and time, how biological structures robustly arise in active matter in the presence of fluctuations and perturbations, and how the variability of shapes is encoded in the genome.

Research Avenue Leader

Frank Jülicher

MPI-PKS | Director of MPI-PKS, Professor for Biophysics

Dynamic processes in cells and tissues

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PoL Groups

Elias Barriga

Research Group Leader

Biophysical Mechanisms of Morphogenesis

hired by PoL

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Michael Brand

TUD CRTD | Professor for Developmental Genetics

Development and Regeneration of the Vertebrate Brain

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Jan Brugués

Chair of Spatiotemporal Organization of Subcellular Structures

Spatiotemporal Organization of Subcellular Structures

hired by PoL

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Otger Campàs

Chair of Tissue Dynamics

Physics of Embryonic Self-Organization and Morphogenesis

hired by PoL

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Natalie Dye

Research Group Leader

Biophysics of Epithelial Growth and Tumorigenesis

hired by PoL

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Elisabeth Fischer-Friedrich

Heisenberg Professor for Mechanics of Active Biomaterials

Mechanics of Active Biomaterials

hired by PoL

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Benjamin Friedrich

Heisenberg Professor for Biological Algorithms

Biological Algorithms: Spatio-Temporal Dynamics of Cells and Tissues

hired by PoL

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Stephan W. Grill

MPI-CBG | Director of MPI-CBG, Professor for Physics of Life

Physics of Life

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Frank Jülicher

MPI-PKS | Director of MPI-PKS, Professor for Biophysics

Dynamic processes in cells and tissues

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Nils Kröger

TUD B CUBE | Professor for Biomimetic Materials

From Molecular Mechanisms of Biomineralization and Bioadhesion to Applications in Nanobiotechnology

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Eugene W. Myers

CSBD | Professor for Computational Molecular Biology

Exploring Cells & Systems via Image Analysis and Customized Microscopy

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Ivo F. Sbalzarini

TUD, CSBD | Professor for Scientific Computing for Systems Biology

The MOSAIC Group: Scientific Computing for Image-based Systems Biology

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Helmut Schießel

Chair of Theoretical Physics of Living Matter

Theoretical Physics of Living Matter

hired by PoL

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Dora Tang

MPI-CBG | Research Group Leader

Dynamic protocellular systems

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Marc Timme

TUD | Professor for Network Dynamics

Network Dynamics

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Xingbo Yang

Research Group Leader

Bioenergetics of Self-Organization

hired by PoL

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Associates and Affiliates

Ricard Alert

MPI-PKS, CSBD | Research Group Leader

The Physics of Living Matter

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Meritxell Huch

MPI-CBG | Director of MPI-CBG, Lise Meitner Max Planck Research Group Leader

Organoids, tissue regeneration and its deregulation in disease

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Christina Kurzthaler

MPI-PKS, CSBD | Research Group Leader

Transport and Flows in Complex Environments

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Carl Modes

MPI-CBG | Research Group Leader

Network Complexity and Systems Biophysics

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Arash Nikoubashman

IPF, TUD Faculty of Physics | Heisenberg Professor for Theory of Biologically Inspired Polymers

Theory of Bio-inspired polymers

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Marko Popović

MPI-PKS, CSBD | Research Group Leader

Order and disorder in driven systems

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Jonathan Rodenfels

MPI-CBG | Research Group Leader

Energetics of Biological Systems

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Jesse Veenvliet

MPI-CBG | Research Group Leader

Stembryogenesis

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Axel Voigt

TUD | Professor for Scientific Computing and Applied Mathematics

Mathematical Modeling and Numerical Simulation of Cells and Systems

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Christoph Zechner

MPI-CBG | Research Group Leader

Adaptive Biosystems

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