Elisabeth Fischer-Friedrich: How cellular surface tension brings cells and tissues into shape
Inaugural Lecture: Heisenberg Professorship for Mechanics of Active Biomaterials
2:50 pm — 4:20 pm
TU Dresden, Recknagel-Bau| Lecture Hall C213
Elisabeth Fischer-Friedrich
ScienceFischer-Friedrich Group
Elisabeth Fischer-Friedrich will give the inaugural speech of her Heisenberg Professorship for Mechanics of Active Biomaterials at the Faculty of Physics.
Just like liquid droplets, cells exhibit a surface tension. In droplets, surface tension stems from interfacial tension associated with the boundary of different phases. However, cellular surface tension corresponds to a mechanical tension in a thin layer of a biopolymer network at the outermost surface of cells. The tension in this network is generated by active processes and is based on the non-equilibrium nature of this living system. I will explain concepts and data of how cells generate this active surface tension. Furthermore, I will give examples of how cells use this actively regulated surface tension in biological processes such as cell division and tissue morphogenesis.