PoL – Physics of Life | Events Archive

Boris Hinz: Myofibroblasts, mechanics and macrophages in tissue repair and fibrosis

Boris' research focuses on tissue repair and regeneration. See also http://hinzlab.com/ 

After his talk, there is the opportunity for a virtual one-to-one meeting with Boris.

Please send me an email if you are interested in talking to him. I will then put together a schedule.

Some recent Papers of Boris are:

Noskovicova, N.*, Schuster, R.*, van Putten, S. M.*, Ezzo, M.*, Koehler, A.*, Boo, S.*, Griggs, D. W., Ruminski, P., and Hinz, B. (2021): Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-beta. Nature Biomedical Engineering (e-pub ahead of print)

Hinz, B. and Lagares, D., (2020) Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases. Nature Reviews Rheumatology 16(1): 11-31

Pakshir, P.*, Alizadehgiashi, M., Wong, B., Coelho, N.M., Chen, X., Gong, Z., Shenoy, V.B., McCulloch, C., and Hinz, B. (2019): Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix. Nature Communications 10: 1850

Li, C.X.*, Talele, N.P.*, Boo, S.*, Knee-Walden, E.*, Koehler, A.*, Kapus, A., Speight, P., Balestrini, J.L.*, Hinz, B. (2017). Micro RNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells. Nature Materials 16(3):379-389

Klingberg, F.*, Chow, M*. L., Koehler, A.*, Boo, S.*, Buscemi, L.*, Quinn, T. M., Costell, M., Alman, B. A., Genot, E., and Hinz, B. (2014). Prestress in the extracellular matrix sensitizes latent TGF-beta1 for activation. J Cell Biol 207, 283-297

Please find further info on the webiste of the CMCB (TU Dresden).